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Aim 1: Demonstrate the accuracy of a rapid phenotyping paradigm in which affected status is established by a) parent-report Social Communication Questionnaire (SCQ); b) teacher.

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Among them are the Checklist of Autism in Toddlers (CHAT), the modified Checklist for Autism in Toddlers (M-CHAT), the Screening Tool for Autism in Two-Year-Olds (STAT), and the Social Communication Questionnaire (SCQ)12 (for kids 4 years of age and older).

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Agency for Healthcare Research and Quality, AstraZeneca Pharmaceuticals, Cephalon Inc, National Institute of Mental Health, Eli Lilly and Company, Pfizer Inc, and Sunovion; served as consultant to Synosia; and received lecture honoraria from AstraZeneca, GlaxoSmithKline, and Bristol-Myers Squibb.

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